Publications

Publications as of November 2022
ORCID.org/0000-0003-1380-4780

(not most highly cited; 18 papers ≥ 100 citations)

• Seiler A, Schneider M, Förster H, Roth S, Wirth EK, Culmsee C, Plesnila N, Kremmer E, Rådmark O, Wurst W, Bornkamm GW, Schweizer U*, Conrad M* (2008) Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death. Cell Metabolism 8, 237–248
  868 citations
  
  
• Schomburg L*, Schweizer U*, Holtmann B, Flohé L, Sendtner M, Köhrle J (2003) Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues. Biochem J  370: 397-402 
  463 citations
  
  
• Ingold I, Berndt C, Schmitt S, Doll S, Poschmann G, Buday K, Roveri A, Peng X, Porto Freitas F, Seibt T, Mehr L, Aichler M, Walch A, Lamp D, Jastroch M, Miyamoto S, Wurst W, Ursini F, Arnér ESJ, Fradejas-Villar N, Schweizer U, Zischka H, Friedmann Angeli JP, Conrad M. (2018) Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis. Cell 172(3):409-422.e21. doi: 10.1016/j.cell.2017.11.048. 
  470 citations
  
  
• Wirth EK, Roth S, Blechschmidt C, Holter SM, Becker L, Racz I, Zimmer A, Klopstock T, Gailus-Durner V, Fuchs H, Wurst W, Naumann T, Bräuer A, de Angelis MH, Köhrle J, Grüters A, Schweizer U (2009) Neuronal 3 ',3,5-Triiodothyronine (T-3) Uptake and Behavioral Phenotype of Mice Deficient in Mct8, the Neuronal T-3 Transporter Mutated in Allan-Herndon-Dudley Syndrome. J Neurosci 29(30): 9439-9449 
  188 citations
  
  
• Wirth EK, Conrad M, Winterer J, Wozny C, Carlson BA, Roth, S, Schmitz D, Bornkamm GW, Coppola V, Tessarollo L, Schomburg L, Kohrle J,Hatfield DL, Schweizer U (2010) Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration. FASEB JOURNAL 24(3):844-852.
  195 citations
  
  
• Schweizer, Ulrich, Schlicker, Christine; Braun, Doreen; et al. (2013) Crystal structure of mammalian selenocysteine-dependent iodothyronine deiodinase suggests a peroxiredoxin-like catalytic mechanism PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA  111(29): 10526-10531  
  81 citations
  
  
• Braun D, Schweizer U. (2017) The Chemical Chaperone Phenylbutyrate Rescues MCT8 Mutations Associated With Milder Phenotypes in Patients With Allan-Herndon-Dudley Syndrome. Endocrinology 158(3):678-691. doi: 10.1210/en.2016-1530.

• Schweizer U and Fabiano M (2022) Selenoproteins in brain development and function. Free Radic Biol Med 190:105-115. 
  doi: 10.1016/j.freeradbiomed.2022.07.022
• Schweizer U, Bohleber S, Zhao W, Fradejas-Villar N. (2021) The Neurobiology of Selenium: Looking Back and to the Future. Front Neurosci. 15:652099. 
  doi: 10.3389/fnins.2021.652099

• Bohleber S, Fradejas-Villar N, Zhao W, Reuter U, Schweizer U. (2022) High-Resolution Ribosome Profiling Reveals Gene-Specific Details of UGA Re-Coding in Selenoprotein Biosynthesis. Biomolecules 12(10):1504. doi: 10.3390/biom12101504.
• Schweizer U, Wirth EK, Klopstock T, Hölter SM, Becker L, Moskovitz J, Grune T, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Köhrle J, Schomburg L. (2022) Seizures, ataxia and parvalbumin-expressing interneurons respond to selenium supply in Selenop-deficient mice. Redox Biol. 57:102490. doi: 10.1016/j.redox.2022.102490
• Rodriguez-Ruiz A, Braun D, Pflug S, Brol A, Sylvester M, Steegborn C, Schweizer U. (2022) Insights into the Mechanism of Human Deiodinase 1. Int J Mol Sci. 23(10):5361. doi: 10.3390/ijms23105361.
• Braun D, Bohleber S, Vatine GD, Svendsen CN, Schweizer U. (2022) Sodium Phenylbutyrate Rescues Thyroid Hormone Transport in Brain Endothelial-Like Cells. Thyroid 32(7):860-870. doi: 10.1089/thy.2021.0643
• Marko HL, Hornig NC, Betz RC, Holterhus PM, Altmüller J, Thiele H, Fabiano M, Schweikert HU, Braun D, Schweizer U. (2022) Genomic variants reducing expression of two endocytic receptors in 46,XY differences of sex development. Hum Mutat. 43(3):420-433. doi: 10.1002/humu.24325
• Fradejas-Villar N, Zhao W, Reuter U, Doengi M, Ingold I, Bohleber S, Conrad M, Schweizer U. (2021) Missense mutation in selenocysteine synthase causes cardio-respiratory failure and perinatal death in mice which can be compensated by selenium-independent GPX4. Redox Biol. 48:102188. doi: 10.1016/j.redox.2021.102188
• Fradejas-Villar N, Bohleber S, Zhao W, Reuter U, Kotter A, Helm M, Knoll R, McFarland R, Taylor RW, Mo Y, Miyauchi K, Sakaguchi Y, Suzuki T, Schweizer U. (2021) The Effect of tRNA[Ser]Sec Isopentenylation on Selenoprotein Expression. Int J Mol Sci. 22(21):11454. doi: 10.3390/ijms222111454.